Vol. 7 Núm. 1 (2015): Revista Ciencia y Salud Virtual
Artículos de Revisión

Linfopoyetina Estromal Tímica y su relación con las enfermedades alérgicas.

Luis Fang Mercado
Corporacion Universitaria Rafael Nuñez
Beatriz Martinez Alfaro
Universidad de Cartagena
Javier Marrugo Cano
Universidad de Cartagena
Publicado June 30, 2015
Palabras clave
  • Linfopoyetina Estromal Tímica,
  • citoquina,
  • rinitis alérgica,
  • pólipos nasales,
  • asma,
  • alergia,
  • células Th2.
  • ...Más
    Menos
Cómo citar
Fang Mercado, L., Martinez Alfaro, B., & Marrugo Cano, J. (2015). Linfopoyetina Estromal Tímica y su relación con las enfermedades alérgicas. Ciencia Y Salud Virtual, 7(1), 59-70. https://doi.org/10.22519/21455333.514

Resumen

La Linfopoyetina Estromal Tímica (TSLP) es una citoquina epitelial, vinculada en el inicio de la respuesta alérgica. Esta citoquina, tiene la capacidad de actuar sobre una gran variedad de poblaciones celulares y cuyos efectos son objeto de estudio en la actualidad. Además, en procesos patológicos que afectan tejido epitelial se han observado niveles elevados de TSLP, como es el caso de la piel de individuos con dermatitis atópica o tejido bronquial de sujetos asmáticos. De otra parte, en diversos estudios de asociación genética, se ha  asociados con el desarrollo de las enfermedades alérgicas. Esta revisión tiene como objetivo, describir a TSLP como una molécula mediadora durante el desarrollo de la respuesta alérgica por parte del sistema inmune; además,  describir su asociación clínica con diversas enfermedades alérgicas.

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